Polymicrobial sepsis is associated with decreased hepatic oxidative phosphorylation and an altered metabolic profile

BACKGROUND: Organ failure in sepsis accounts for significant mortality worldwide. Mitochondrial and metabolic responses are central to the overall response of the cell, and thus of the organ and organism. Adaptive responses in metabolism are critical to the recovery at the cellular level. The purpos...

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Hauptverfasser: Whelan, Sean P., Carchman, Evie H., Kautza, Benjamin, Nassour, Ibrahim, Mollen, Kevin, Escobar, Daniel, Gomez, Hernando, Rosengart, Matthew A., Shiva, Sruti, Zuckerbraun, Brian S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4027053/
https://ncbi.nlm.nih.gov/pubmed/24054495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jss.2013.08.007
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