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Genus level analysis of PKS-NRPS and NRPS-PKS hybrids reveals their origin in Aspergilli
BACKGROUND: Filamentous fungi produce a vast amount of bioactive secondary metabolites (SMs) synthesized by e.g. hybrid polyketide synthase-nonribosomal peptide synthetase enzymes (PKS-NRPS; NRPS-PKS). While their domain structure suggests a common ancestor with other SM proteins, their evolutionary...
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| Publicado en: | BMC Genomics |
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| Autores principales: | , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
BioMed Central
2019
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6854747/ https://ncbi.nlm.nih.gov/pubmed/31722662 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-019-6114-2 |
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