Nonlinear Biosynthetic Assembly of Alpiniamide by a Hybrid cis/trans-AT PKS-NRPS

Alpiniamide A is a linear polyketide produced by Streptomyces endophytic bacteria. Despite its relatively simple chemical structure suggestive of a linear assembly line biosynthetic construction involving a hybrid polyketide synthase-nonribosomal peptide synthetase enzymatic protein machine, we repo...

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發表在:ACS Chem Biol
Main Authors: Sigrist, Renata, Luhavaya, Hanna, McKinnie, Shaun M. K., da Silva, Amanda Ferreira, Jurberg, Igor D., Moore, Bradley S., de Oliveira, Luciana Gonzaga
格式: Artigo
語言:Inglês
出版: 2020
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7286424/
https://ncbi.nlm.nih.gov/pubmed/32195572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.0c00081
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