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Linker Flexibility Facilitates Module Exchange in Fungal Hybrid PKS-NRPS Engineering
Polyketide synthases (PKSs) and nonribosomal peptide synthetases (NRPSs) each give rise to a vast array of complex bioactive molecules with further complexity added by the existence of natural PKS-NRPS fusions. Rational genetic engineering for the production of natural product derivatives is desirab...
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| Veröffentlicht in: | PLoS One |
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| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4994942/ https://ncbi.nlm.nih.gov/pubmed/27551732 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0161199 |
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