HIV-1 integrase inhibitors targeting various DDE transposases: Retroviral integration versus RAG-mediated recombination

Transposases are ubiquitous mobile genetic elements responsible for genome development, driving rearrangements, such as insertions, deletions and translocations. Across species evolution, some transposases are tamed by their host and are made part of complex cellular systems. The proliferation of re...

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Detalhes bibliográficos
Publicado no:Mol Med Rep
Main Authors: Mușat, Mihaela Georgiana, Nițulescu, George Mihai, Surleac, Marius, Tsatsakis, Aristidis, Spandidos, Demetrios A., Margină, Denisa
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2019
Assuntos:
Review
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6854553/
https://ncbi.nlm.nih.gov/pubmed/31702817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2019.10777
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