HIV-1 integrase inhibitors targeting various DDE transposases: Retroviral integration versus RAG-mediated recombination

Transposases are ubiquitous mobile genetic elements responsible for genome development, driving rearrangements, such as insertions, deletions and translocations. Across species evolution, some transposases are tamed by their host and are made part of complex cellular systems. The proliferation of re...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Mol Med Rep
Prif Awduron: Mușat, Mihaela Georgiana, Nițulescu, George Mihai, Surleac, Marius, Tsatsakis, Aristidis, Spandidos, Demetrios A., Margină, Denisa
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: D.A. Spandidos 2019
Pynciau:
Review
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6854553/
https://ncbi.nlm.nih.gov/pubmed/31702817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2019.10777
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