Akt inhibitors in cancer treatment: The long journey from drug discovery to clinical use (Review)

Targeted cancer therapies are used to inhibit the growth, progression, and metastasis of the tumor by interfering with specific molecular targets and are currently the focus of anticancer drug development. Protein kinase B, also known as Akt, plays a central role in many types of cancer and has been...

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Vydáno v:Int J Oncol
Hlavní autoři: NITULESCU, GEORGE MIHAI, MARGINA, DENISA, JUZENAS, PETRAS, PENG, QIAN, OLARU, OCTAVIAN TUDOREL, SALOUSTROS, EMMANOUIL, FENGA, CONCETTINA, SPANDIDOS, DEMETRIOS A., LIBRA, MASSIMO, TSATSAKIS, ARISTIDIS M.
Médium: Artigo
Jazyk:Inglês
Vydáno: D.A. Spandidos 2015
Témata:
Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4750533/
https://ncbi.nlm.nih.gov/pubmed/26698230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijo.2015.3306
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