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Targeting Bacterial Sortases in Search of Anti-virulence Therapies with Low Risk of Resistance Development

Increasingly ineffective antibiotics and rapid spread of multi- and pan-resistant bacteria represent a global health threat; hence, the need of developing new antimicrobial medicines. A first step in this direction is identifying new molecular targets, such as virulence factors. Sortase A represents...

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Detalhes bibliográficos
Publicado no:Pharmaceuticals (Basel)
Main Authors: Nitulescu, Georgiana, Margina, Denisa, Zanfirescu, Anca, Olaru, Octavian Tudorel, Nitulescu, George Mihai
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8147154/
https://ncbi.nlm.nih.gov/pubmed/33946434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph14050415
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