Mapping the perturbome network of cellular perturbations

Drug combinations provide effective treatments for diverse diseases, but also represent a major cause of adverse reactions. Currently there is no systematic understanding of how the complex cellular perturbations induced by different drugs influence each other. Here, we introduce a mathematical fram...

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Udgivet i:Nat Commun
Main Authors: Caldera, Michael, Müller, Felix, Kaltenbrunner, Isabel, Licciardello, Marco P., Lardeau, Charles-Hugues, Kubicek, Stefan, Menche, Jörg
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6853941/
https://ncbi.nlm.nih.gov/pubmed/31723137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-13058-9
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