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Cellular network perturbations by disease-associated variants

Genetic and genome-wide association studies (GWAS) have identified a myriad of human disease-associated genomic variants. However, these studies do not reveal the mechanisms by which these variants perturb cellular networks, a necessary step to intervene and improve disease outcomes. This has been c...

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Bibliographische Detailangaben
Veröffentlicht in:Curr Opin Syst Biol
Hauptverfasser: Sewell, Jared A., Fuxman Bass, Juan I.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5646826/
https://ncbi.nlm.nih.gov/pubmed/29057377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coisb.2017.04.009
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