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Cellular network perturbations by disease-associated variants

Genetic and genome-wide association studies (GWAS) have identified a myriad of human disease-associated genomic variants. However, these studies do not reveal the mechanisms by which these variants perturb cellular networks, a necessary step to intervene and improve disease outcomes. This has been c...

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Bibliografiska uppgifter
I publikationen:Curr Opin Syst Biol
Huvudupphovsmän: Sewell, Jared A., Fuxman Bass, Juan I.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2017
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5646826/
https://ncbi.nlm.nih.gov/pubmed/29057377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coisb.2017.04.009
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