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Mapping the perturbome network of cellular perturbations

Drug combinations provide effective treatments for diverse diseases, but also represent a major cause of adverse reactions. Currently there is no systematic understanding of how the complex cellular perturbations induced by different drugs influence each other. Here, we introduce a mathematical fram...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nat Commun
Prif Awduron: Caldera, Michael, Müller, Felix, Kaltenbrunner, Isabel, Licciardello, Marco P., Lardeau, Charles-Hugues, Kubicek, Stefan, Menche, Jörg
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2019
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6853941/
https://ncbi.nlm.nih.gov/pubmed/31723137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-13058-9
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