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Multisite phosphorylation drives phenotypic variation in (p)ppGpp synthetase-dependent antibiotic tolerance

Isogenic populations of cells exhibit phenotypic variability that has specific physiological consequences. Individual bacteria within a population can differ in antibiotic tolerance, but whether this variability can be regulated or is generally an unavoidable consequence of stochastic fluctuations i...

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Bibliografiske detaljer
Udgivet i:Nat Commun
Main Authors: Libby, Elizabeth A., Reuveni, Shlomi, Dworkin, Jonathan
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6853874/
https://ncbi.nlm.nih.gov/pubmed/31723135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-13127-z
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