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Birth and Resuscitation of (p)ppGpp Induced Antibiotic Tolerant Persister Cells

Transient antibiotic treatment typically eradicates most sensitive bacteria except a few survivors called persisters. The second messenger (p)ppGpp plays a key role in persister formation in Escherichia coli populations but the underlying mechanisms have remained elusive. In this study we induced (p...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Svenningsen, Mikkel Skjoldan, Veress, Alexandra, Harms, Alexander, Mitarai, Namiko, Semsey, Szabolcs
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6465370/
https://ncbi.nlm.nih.gov/pubmed/30988388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-42403-7
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