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Synchronized switching of multiple toxin–antitoxin modules by (p)ppGpp fluctuation

Toxin–antitoxin (TA) loci are widespread in bacteria including important pathogenic species. Recent studies suggest that TA systems play a key role in persister formation. However, the persistence phenotype shows only weak dependence on the number of TA systems, i.e. they are functionally redundant....

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Tian, Chengzhe, Semsey, Szabolcs, Mitarai, Namiko
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5737467/
https://ncbi.nlm.nih.gov/pubmed/28854732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx552
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