The (p)ppGpp Synthetase RSH Mediates Stationary-Phase Onset and Antibiotic Stress Survival in Clostridioides difficile

The human pathogen Clostridioides difficile is increasingly tolerant of multiple antibiotics and causes infections with a high rate of recurrence, creating an urgent need for new preventative and therapeutic strategies. The stringent response, a universal bacterial response to extracellular stress,...

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Vydáno v:J Bacteriol
Hlavní autoři: Pokhrel, Astha, Poudel, Asia, Castro, Kory B., Celestine, Michael J., Oludiran, Adenrele, Rinehold, Alden J., Resek, Anthony M., Mhanna, Mariam A., Purcell, Erin B.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2020
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7484180/
https://ncbi.nlm.nih.gov/pubmed/32661079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00377-20
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