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The C-terminal dimerization domain of the respiratory mucin MUC5B functions in mucin stability and intracellular packaging before secretion
Mucin 5B (MUC5B) has an essential role in mucociliary clearance that protects the pulmonary airways. Accordingly, knowledge of MUC5B structure and its interactions with itself and other proteins is critical to better understand airway mucus biology and improve the management of lung diseases such as...
Enregistré dans:
Publié dans: | J Biol Chem |
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Auteurs principaux: | , , , , , , , |
Format: | Artigo |
Langue: | Inglês |
Publié: |
American Society for Biochemistry and Molecular Biology
2019
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Sujets: | |
Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6851316/ https://ncbi.nlm.nih.gov/pubmed/31570524 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.010771 |
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