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The C-terminal dimerization domain of the respiratory mucin MUC5B functions in mucin stability and intracellular packaging before secretion

Mucin 5B (MUC5B) has an essential role in mucociliary clearance that protects the pulmonary airways. Accordingly, knowledge of MUC5B structure and its interactions with itself and other proteins is critical to better understand airway mucus biology and improve the management of lung diseases such as...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Ridley, Caroline, Lockhart-Cairns, Michael P., Collins, Richard F., Jowitt, Thomas A., Subramani, Durai B., Kesimer, Mehmet, Baldock, Clair, Thornton, David J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6851316/
https://ncbi.nlm.nih.gov/pubmed/31570524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.010771
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