Site-specific O-Glycosylation on the MUC2 Mucin Protein Inhibits Cleavage by the Porphyromonas gingivalis Secreted Cysteine Protease (RgpB)

The colonic epithelial surface is protected by an inner mucus layer that the commensal microflora cannot penetrate. We previously demonstrated that Entamoeba histolytica secretes a protease capable of dissolving this layer that is required for parasite penetration. Here, we asked whether there are b...

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Detalhes bibliográficos
Main Authors: van der Post, Sjoerd, Subramani, Durai B., Bäckström, Malin, Johansson, Malin E. V., Vester-Christensen, Malene B., Mandel, Ulla, Bennett, Eric P., Clausen, Henrik, Dahlén, Gunnar, Sroka, Aneta, Potempa, Jan, Hansson, Gunnar C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Glycobiology and Extracellular Matrices
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3656315/
https://ncbi.nlm.nih.gov/pubmed/23546879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.459479
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