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Kgp and RgpB, but Not RgpA, Are Important for Porphyromonas gingivalis Virulence in the Murine Periodontitis Model

The contributions of three proteinase genes (rgpA, rgpB, and kgp) to the virulence of Porphyromonas gingivalis W50 were investigated in the murine periodontitis model. Mice were orally inoculated with eight doses (1 × 10(10) cells per dose) of rgpA, rgpB, kgp, rgpA rgpB, or rgpA rgpB kgp isogenic mu...

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Detalhes bibliográficos
Main Authors: Pathirana, Rishi D., O'Brien-Simpson, Neil M., Brammar, Gail C., Slakeski, Nada, Reynolds, Eric C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1828545/
https://ncbi.nlm.nih.gov/pubmed/17220315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01627-06
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