Assembly of the Respiratory Mucin MUC5B: A NEW MODEL FOR A GEL-FORMING MUCIN

Mucins are essential components in mucus gels that form protective barriers at all epithelial surfaces, but much remains unknown about their assembly, intragranular organization, and post-secretion unfurling to form mucus. MUC5B is a major polymeric mucin expressed by respiratory epithelia, and we i...

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Detalhes bibliográficos
Main Authors: Ridley, Caroline, Kouvatsos, Nikos, Raynal, Bertrand D., Howard, Marj, Collins, Richard F., Desseyn, Jean-Luc, Jowitt, Thomas A., Baldock, Clair, Davis, C. William, Hardingham, Timothy E., Thornton, David J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Glycobiology and Extracellular Matrices
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4047408/
https://ncbi.nlm.nih.gov/pubmed/24778189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.566679
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