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Biosynthesis of the polymeric gel-forming mucin MUC5B

MUC5B is a major polymeric mucin in the airway mucus gel and is an essential component of innate defense of the respiratory epithelium. Knowledge of the synthesis and intracellular processing of MUC5B is incomplete. We investigated the molecular details of MUC5B assembly in primary human bronchial e...

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Detalhes bibliográficos
Publicado no:Am J Physiol Lung Cell Mol Physiol
Main Authors: Ridley, Caroline, Kirkham, Sara, Williamson, Sally J., Davis, C. William, Woodman, Philip, Thornton, David J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4896102/
https://ncbi.nlm.nih.gov/pubmed/26993521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00046.2016
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