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MUC5B Is the Major Mucin in the Gel Phase of Sputum in Chronic Obstructive Pulmonary Disease

Rationale: Overproduction of mucus is a contributory factor in the progression of chronic obstructive pulmonary disease (COPD). The polymeric mucins are major macromolecules in the secretion. Therefore, we hypothesized that the polymeric mucin composition or properties may be different in the sputum...

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Detalhes bibliográficos
Main Authors: Kirkham, Sara, Kolsum, Umme, Rousseau, Karine, Singh, Dave, Vestbo, Jørgen, Thornton, David J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2643221/
https://ncbi.nlm.nih.gov/pubmed/18776153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.200803-391OC
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