Biosynthesis of the polymeric gel-forming mucin MUC5B

MUC5B is a major polymeric mucin in the airway mucus gel and is an essential component of innate defense of the respiratory epithelium. Knowledge of the synthesis and intracellular processing of MUC5B is incomplete. We investigated the molecular details of MUC5B assembly in primary human bronchial e...

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Bibliographic Details
Published in:Am J Physiol Lung Cell Mol Physiol
Main Authors: Ridley, Caroline, Kirkham, Sara, Williamson, Sally J., Davis, C. William, Woodman, Philip, Thornton, David J.
Format: Artigo
Language:Inglês
Published: American Physiological Society 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4896102/
https://ncbi.nlm.nih.gov/pubmed/26993521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00046.2016
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