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Activated cholangiocytes release macrophage-polarizing extracellular vesicles bearing the DAMP S100A11

In mouse models of biliary tract diseases, macrophages are recruited to the periductal milieu and promote injury and cholestasis. Although cell necrosis with release of biomolecules termed damage-associated molecular patterns (DAMPs) promotes recruitment and activation of macrophages, necrosis was n...

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Detalhes bibliográficos
Publicado no:Am J Physiol Cell Physiol
Main Authors: Katsumi, Tomohiro, Guicciardi, Maria Eugenia, Azad, Adiba, Bronk, Steven F., Krishnan, Anuradha, Gores, Gregory J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6851002/
https://ncbi.nlm.nih.gov/pubmed/31365294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00250.2019
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