Activated cholangiocytes release macrophage-polarizing extracellular vesicles bearing the DAMP S100A11

In mouse models of biliary tract diseases, macrophages are recruited to the periductal milieu and promote injury and cholestasis. Although cell necrosis with release of biomolecules termed damage-associated molecular patterns (DAMPs) promotes recruitment and activation of macrophages, necrosis was n...

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Publicado en:Am J Physiol Cell Physiol
Autores principales: Katsumi, Tomohiro, Guicciardi, Maria Eugenia, Azad, Adiba, Bronk, Steven F., Krishnan, Anuradha, Gores, Gregory J.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Physiological Society 2019
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6851002/
https://ncbi.nlm.nih.gov/pubmed/31365294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00250.2019
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