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Activated cholangiocytes release macrophage-polarizing extracellular vesicles bearing the DAMP S100A11

In mouse models of biliary tract diseases, macrophages are recruited to the periductal milieu and promote injury and cholestasis. Although cell necrosis with release of biomolecules termed damage-associated molecular patterns (DAMPs) promotes recruitment and activation of macrophages, necrosis was n...

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Pubblicato in:Am J Physiol Cell Physiol
Autori principali: Katsumi, Tomohiro, Guicciardi, Maria Eugenia, Azad, Adiba, Bronk, Steven F., Krishnan, Anuradha, Gores, Gregory J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6851002/
https://ncbi.nlm.nih.gov/pubmed/31365294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00250.2019
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