Cholesterol accessibility at the ciliary membrane controls hedgehog signaling

Previously we proposed that transmission of the hedgehog signal across the plasma membrane by Smoothened is triggered by its interaction with cholesterol (Luchetti et al., 2016). But how is cholesterol, an abundant lipid, regulated tightly enough to control a signaling system that can cause birth de...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Izdano u:eLife
Glavni autori: Kinnebrew, Maia, Iverson, Ellen J, Patel, Bhaven B, Pusapati, Ganesh V, Kong, Jennifer H, Johnson, Kristen A, Luchetti, Giovanni, Eckert, Kaitlyn M, McDonald, Jeffrey G, Covey, Douglas F, Siebold, Christian, Radhakrishnan, Arun, Rohatgi, Rajat
Format: Artigo
Jezik:Inglês
Izdano: eLife Sciences Publications, Ltd 2019
Teme:
Cell Biology
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6850779/
https://ncbi.nlm.nih.gov/pubmed/31657721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.50051
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!

Similar Items