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5-Aza-CdR Regulates RASSF1A By Inhibiting DNMT1 To Affect Colon Cancer Cell Proliferation, Migration And Apoptosis

OBJECTIVE: To evaluate 5-Aza-CdR’s inhibited effects on migration, proliferation, and apoptosis in colon cancer cells and its potential mechanisms. METHODS: HCT-116, SW480, and SW620 were divided into HCT116 group, HCT116+5-Aza-CdR group, SW480 group, SW480+5-Aza-CdR group, SW620 group and SW620+5-A...

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Détails bibliographiques
Publié dans:Cancer Manag Res
Auteurs principaux: Chen, Jinyuan, Wu, Lixiang, Xu, Hong, Cheng, Shubang
Format: Artigo
Langue:Inglês
Publié: Dove 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6850683/
https://ncbi.nlm.nih.gov/pubmed/31807076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CMAR.S229726
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