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Regulation of demethylation and re-expression of RASSF1A gene in gastric cancer cell lines by combined treatment of 5-Aza-CdR and NaB

AIM: To investigate the changes of methylation state and expression of RASSF1A gene in human gastric cancer cell lines SGC7901 and BGC823 which were treated in vitro with demethylating agent 5-Aza-CdR in combination with histone deacetylase inhibitor NaB. METHODS: After SGC7901 and BGC823 cells were...

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Main Authors: Shen, Wen-Jing, Dai, Dong-Qiu, Teng, Yue, Liu, Hong-Bo
Formato: Artigo
Idioma:Inglês
Publicado: The WJG Press and Baishideng 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2681152/
https://ncbi.nlm.nih.gov/pubmed/18203293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.14.595
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