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5-Aza-CdR Regulates RASSF1A By Inhibiting DNMT1 To Affect Colon Cancer Cell Proliferation, Migration And Apoptosis

OBJECTIVE: To evaluate 5-Aza-CdR’s inhibited effects on migration, proliferation, and apoptosis in colon cancer cells and its potential mechanisms. METHODS: HCT-116, SW480, and SW620 were divided into HCT116 group, HCT116+5-Aza-CdR group, SW480 group, SW480+5-Aza-CdR group, SW620 group and SW620+5-A...

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Detalhes bibliográficos
Publicado no:Cancer Manag Res
Main Authors: Chen, Jinyuan, Wu, Lixiang, Xu, Hong, Cheng, Shubang
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6850683/
https://ncbi.nlm.nih.gov/pubmed/31807076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CMAR.S229726
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