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The RASSF1 Gene and the Opposing Effects of the RASSF1A and RASSF1C Isoforms on Cell Proliferation and Apoptosis

RASSF1A has been demonstrated to be a tumor suppressor, while RASSF1C is now emerging as a growth promoting protein in breast and lung cancer cells. To further highlight the dual functionality of the RASSF1 gene, we have compared the effects of RASSF1A and RASSF1C on cell proliferation and apoptosis...

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Detalhes bibliográficos
Main Authors: Reeves, Mark E., Firek, Matthew, Chen, Shin-Tai, Amaar, Yousef
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3845702/
https://ncbi.nlm.nih.gov/pubmed/24327924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/145096
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