Phosphatase inhibitor PPP1R11 modulates resistance of human T cells toward Treg‐mediated suppression of cytokine expression

Regulatory T cells (Tregs) act as indispensable unit for maintaining peripheral immune tolerance mainly by regulating effector T cells. T cells resistant to suppression by Tregs pose therapeutic challenges in the treatment of autoimmune diseases, while augmenting susceptibility to suppression may be...

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Detalhes bibliográficos
Publicado no:J Leukoc Biol
Main Authors: Joshi, Rubin N., Fernandes, Sunjay Jude, Shang, Ming‐Mei, Kiani, Narsis A., Gomez‐Cabrero, David, Tegnér, Jesper, Schmidt, Angelika
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Receptors, Signal Transduction, & Genes
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6850362/
https://ncbi.nlm.nih.gov/pubmed/30882958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/JLB.2A0618-228R
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