Phosphoproteomics Reveals Regulatory T Cell-Mediated DEF6 Dephosphorylation That Affects Cytokine Expression in Human Conventional T Cells

Regulatory T cells (Tregs) control key events of immune tolerance, primarily by suppression of effector T cells. We previously revealed that Tregs rapidly suppress T cell receptor (TCR)-induced calcium store depletion in conventional CD4(+)CD25(−) T cells (Tcons) independently of IP(3) levels, conse...

Full description

Saved in:
Bibliographic Details
Published in:Front Immunol
Main Authors: Joshi, Rubin N., Binai, Nadine A., Marabita, Francesco, Sui, Zhenhua, Altman, Amnon, Heck, Albert J. R., Tegnér, Jesper, Schmidt, Angelika
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2017
Subjects:
Immunology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5622166/
https://ncbi.nlm.nih.gov/pubmed/28993769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.01163
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items