Phosphoproteomics Reveals Regulatory T Cell-Mediated DEF6 Dephosphorylation That Affects Cytokine Expression in Human Conventional T Cells

Regulatory T cells (Tregs) control key events of immune tolerance, primarily by suppression of effector T cells. We previously revealed that Tregs rapidly suppress T cell receptor (TCR)-induced calcium store depletion in conventional CD4(+)CD25(−) T cells (Tcons) independently of IP(3) levels, conse...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Joshi, Rubin N., Binai, Nadine A., Marabita, Francesco, Sui, Zhenhua, Altman, Amnon, Heck, Albert J. R., Tegnér, Jesper, Schmidt, Angelika
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5622166/
https://ncbi.nlm.nih.gov/pubmed/28993769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.01163
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