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In Vitro Differentiation of Human CD4(+)FOXP3(+) Induced Regulatory T Cells (iTregs) from Naïve CD4(+) T Cells Using a TGF-β-containing Protocol
Regulatory T cells (Tregs) are an integral part of peripheral tolerance, suppressing immune reactions against self-structures and thus preventing autoimmune diseases. Clinical approaches to adoptively transfer Tregs, or to deplete Tregs in cancer, are underway with promising first outcomes. Because...
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| Publicado no: | J Vis Exp |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MyJove Corporation
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5226637/ https://ncbi.nlm.nih.gov/pubmed/28060341 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/55015 |
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