Comparative Analysis of Protocols to Induce Human CD4+Foxp3+ Regulatory T Cells by Combinations of IL-2, TGF-beta, Retinoic Acid, Rapamycin and Butyrate

Regulatory T cells (Tregs) suppress other immune cells and are critical mediators of peripheral tolerance. Therapeutic manipulation of Tregs is subject to numerous clinical investigations including trials for adoptive Treg transfer. Since the number of naturally occurring Tregs (nTregs) is minute, i...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Schmidt, Angelika, Eriksson, Matilda, Shang, Ming-Mei, Weyd, Heiko, Tegnér, Jesper
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4757416/
https://ncbi.nlm.nih.gov/pubmed/26886923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0148474
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