Characterization of Protective Human CD4(+)CD25(+) FOXP3(+) Regulatory T Cells Generated with IL-2, TGF-β and Retinoic Acid

BACKGROUND: Protective CD4+CD25+ regulatory T cells bearing the Forkhead Foxp3 transcription factor can now be divided into three subsets: Endogenous thymus-derived cells, those induced in the periphery, and another subset induced ex-vivo with pharmacological amounts of IL-2 and TGF-β. Unfortunately...

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Bibliografiska uppgifter
Huvudupphovsmän: Lu, Ling, Zhou, Xiaohui, Wang, Julie, Zheng, Song Guo, Horwitz, David A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2010
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3003689/
https://ncbi.nlm.nih.gov/pubmed/21179414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0015150
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