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Contrasting roles for all-trans retinoic acid in TGF-β–mediated induction of Foxp3 and Il10 genes in developing regulatory T cells

Extrathymic induction of regulatory T (T reg) cells is essential to the regulation of effector T cell responses in the periphery. In addition to Foxp3, T reg cell expression of suppressive cytokines, such as IL-10, is essential for peripheral tolerance, particularly in the intestines. TGF-β has been...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Maynard, Craig L., Hatton, Robin D., Helms, Whitney S., Oliver, James R., Stephensen, Charles B., Weaver, Casey T.
פורמט: Artigo
שפה:Inglês
יצא לאור: The Rockefeller University Press 2009
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2646562/
https://ncbi.nlm.nih.gov/pubmed/19204112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20080950
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