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AAV-mediated delivery of CRISPR/Cas systems for genome engineering in mammalian cells

The CRISPR/Cas9 system has emerged as a highly versatile platform for inducing targeted genome modifications into mammalian cells and model organisms. However, fully capitalizing on the therapeutic potential for this system requires its safe and efficient delivery into relevant cell types. Adeno-ass...

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Detalhes bibliográficos
Publicado no:Cold Spring Harb Protoc
Main Authors: Gaj, Thomas, Schaffer, David V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6850213/
https://ncbi.nlm.nih.gov/pubmed/27803249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/pdb.prot086868
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