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Engineered AAV vectors for improved central nervous system gene delivery

Adeno-associated viruses (AAV) are non-pathogenic members of the Parvoviridae family that are being harnessed as delivery vehicles for both basic research and increasingly successful clinical gene therapy. To address a number of delivery shortcomings with natural AAV variants, we have developed and...

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Detalles Bibliográficos
Publicado en:Neurogenesis (Austin)
Main Authors: A Kotterman, Melissa, Schaffer, David V
Formato: Artigo
Idioma:Inglês
Publicado: Taylor & Francis 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4973602/
https://ncbi.nlm.nih.gov/pubmed/27606332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23262133.2015.1122700
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