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TACI expression and plasma cell differentiation are impaired in the absence of functional IκBNS

Impaired classical NF‐κB pathway signaling causes reduced antibody responses to T‐independent (TI) antigens. We investigated the potential reasons for defective TI responses in mice lacking the atypical inhibitory kappa B (IκB) protein of the NF‐κB pathway, IκBNS. Analyses of the plasma cell compart...

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Detalhes bibliográficos
Publicado no:Immunol Cell Biol
Main Authors: Khoenkhoen, Sharesta, Erikson, Elina, Ádori, Monika, Stark, Julian M, Scholz, Jean L, Cancro, Michael P, Pedersen, Gabriel K, Karlsson Hedestam, Gunilla B
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6850186/
https://ncbi.nlm.nih.gov/pubmed/30597621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imcb.12228
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