TACI expression and plasma cell differentiation are impaired in the absence of functional IκBNS

Impaired classical NF‐κB pathway signaling causes reduced antibody responses to T‐independent (TI) antigens. We investigated the potential reasons for defective TI responses in mice lacking the atypical inhibitory kappa B (IκB) protein of the NF‐κB pathway, IκBNS. Analyses of the plasma cell compart...

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Vydáno v:Immunol Cell Biol
Hlavní autoři: Khoenkhoen, Sharesta, Erikson, Elina, Ádori, Monika, Stark, Julian M, Scholz, Jean L, Cancro, Michael P, Pedersen, Gabriel K, Karlsson Hedestam, Gunilla B
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2019
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Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6850186/
https://ncbi.nlm.nih.gov/pubmed/30597621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imcb.12228
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