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B-1a transitional cells are phenotypically distinct and are lacking in mice deficient in IκBNS
B-1 cells mediate early protection against infection by responding to T cell-independent (TI) antigens found on the surface of various pathogens. Mice with impaired expression of the atypical IκB protein IκBNS have markedly reduced frequencies of B-1 cells. We used a mouse strain with dysfunctional...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4191775/ https://ncbi.nlm.nih.gov/pubmed/25228759 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1415866111 |
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