Spontaneous atopic dermatitis in mice with a defective skin barrier is independent of ILC2 and mediated by IL‐1β

BACKGROUND: Atopic dermatitis (AD) is one of the most common skin diseases with a multifactorial etiology. Mutations leading to loss of skin barrier function are associated with the development of AD with group 2 innate lymphoid cells (ILC2) promoting acute skin inflammation. Filaggrin‐mutant (Flg(f...

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Publicado no:Allergy
Main Authors: Schwartz, Christian, Moran, Tara, Saunders, Sean P., Kaszlikowska, Agnieszka, Floudas, Achilleas, Bom, Joana, Nunez, Gabriel, Iwakura, Yoichiro, O’Neill, Luke, Irvine, Alan D., McKenzie, Andrew N. J., Ogg, Graham, Walsh, Patrick T., Demengeot, Jocelyne, Fallon, Padraic G.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
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ORIGINAL ARTICLES
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6850072/
https://ncbi.nlm.nih.gov/pubmed/30937919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/all.13801
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