Spontaneous atopic dermatitis in mice with a defective skin barrier is independent of ILC2 and mediated by IL‐1β

BACKGROUND: Atopic dermatitis (AD) is one of the most common skin diseases with a multifactorial etiology. Mutations leading to loss of skin barrier function are associated with the development of AD with group 2 innate lymphoid cells (ILC2) promoting acute skin inflammation. Filaggrin‐mutant (Flg(f...

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Udgivet i:Allergy
Main Authors: Schwartz, Christian, Moran, Tara, Saunders, Sean P., Kaszlikowska, Agnieszka, Floudas, Achilleas, Bom, Joana, Nunez, Gabriel, Iwakura, Yoichiro, O’Neill, Luke, Irvine, Alan D., McKenzie, Andrew N. J., Ogg, Graham, Walsh, Patrick T., Demengeot, Jocelyne, Fallon, Padraic G.
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2019
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ORIGINAL ARTICLES
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6850072/
https://ncbi.nlm.nih.gov/pubmed/30937919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/all.13801
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