A role for IL-25 and IL-33–driven type-2 innate lymphoid cells in atopic dermatitis

Type 2 innate lymphoid cells (ILC2s, nuocytes, NHC) require RORA and GATA3 for their development. We show that human ILC2s express skin homing receptors and infiltrate the skin after allergen challenge, where they produce the type 2 cytokines IL-5 and IL-13. Skin-derived ILC2s express the IL-33 rece...

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書誌詳細
主要な著者: Salimi, Maryam, Barlow, Jillian L., Saunders, Sean P., Xue, Luzheng, Gutowska-Owsiak, Danuta, Wang, Xinwen, Huang, Li-Chieh, Johnson, David, Scanlon, Seth T., McKenzie, Andrew N.J., Fallon, Padraic G., Ogg, Graham S.
フォーマット: Artigo
言語:Inglês
出版事項: The Rockefeller University Press 2013
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3865470/
https://ncbi.nlm.nih.gov/pubmed/24323357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20130351
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