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A role for IL-25 and IL-33–driven type-2 innate lymphoid cells in atopic dermatitis
Type 2 innate lymphoid cells (ILC2s, nuocytes, NHC) require RORA and GATA3 for their development. We show that human ILC2s express skin homing receptors and infiltrate the skin after allergen challenge, where they produce the type 2 cytokines IL-5 and IL-13. Skin-derived ILC2s express the IL-33 rece...
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Main Authors: | , , , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
The Rockefeller University Press
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3865470/ https://ncbi.nlm.nih.gov/pubmed/24323357 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20130351 |
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