Induction of activated T follicular helper cells is critical for anti-FVIII inhibitor development in hemophilia A mice

The development of neutralizing anti-FVIII antibodies (inhibitors) is a major complication of FVIII protein replacement therapy in patients with hemophilia A (HA). Although multiple lines of evidence indicate that the immune response against FVIII is CD4 T-cell–dependent and many FVIII-derived CD4 e...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Blood Adv
Hlavní autoři: Jing, Weiqing, Chen, Juan, Cai, Yuanhua, Chen, Yingyu, Schroeder, Jocelyn A., Johnson, Bryon D., Cui, Weiguo, Shi, Qizhen
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2019
Témata:
Thrombosis and Hemostasis
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6849959/
https://ncbi.nlm.nih.gov/pubmed/31648333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2019000650
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky