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Platelet-Targeted FVIII Gene Therapy Restores Hemostasis and Induces Immune Tolerance for Hemophilia A

Platelets are small anucleated blood components primarily described as playing a fundamental role in hemostasis and thrombosis. Over the last decades, increasing evidence has demonstrated the role of platelets in modulating inflammatory reactions and immune responses. Platelets harbor several specia...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Cai, Yuanhua, Shi, Qizhen
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7303294/
https://ncbi.nlm.nih.gov/pubmed/32595633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.00964
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