Dimethyl fumarate impairs differentiated B cells and fosters central nervous system integrity in treatment of multiple sclerosis

In multiple sclerosis (MS), the effect of dimethyl fumarate (DMF) treatment is primarily attributed to its capacity to dampen pathogenic T cells. Here, we tested whether DMF also modulates B cells, which are newly recognized key players in MS, and to which extent DMF restricts ongoing loss of oligod...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Brain Pathol
Päätekijät: Traub, Jan, Traffehn, Sarah, Ochs, Jasmin, Häusser‐Kinzel, Silke, Stephan, Schirin, Scannevin, Robert, Brück, Wolfgang, Metz, Imke, Weber, Martin S.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: John Wiley and Sons Inc. 2019
Aiheet:
Research Articles
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6849574/
https://ncbi.nlm.nih.gov/pubmed/30706542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bpa.12711
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