Natalizumab promotes activation and pro-inflammatory differentiation of peripheral B cells in multiple sclerosis patients

BACKGROUND: In the past, multiple sclerosis (MS) medications have been primarily designed to modulate T cell properties. Based on the emerging concept that B cells are equally important for the propagation of MS, we compared the effect of four commonly used, primarily T cell-targeting MS medications...

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Dettagli Bibliografici
Pubblicato in:J Neuroinflammation
Autori principali: Traub, Jan W., Pellkofer, Hannah L., Grondey, Katja, Seeger, Ira, Rowold, Christoph, Brück, Wolfgang, Husseini, Leila, Häusser-Kinzel, Silke, Weber, Martin S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2019
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6858649/
https://ncbi.nlm.nih.gov/pubmed/31733652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-019-1593-2
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