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B cells reappear less mature and more activated after their anti-CD20–mediated depletion in multiple sclerosis

B cell depletion via anti-CD20 antibodies is a highly effective treatment for multiple sclerosis (MS). However, little is known about the maturation/activation stage of the returning B cell population after treatment cessation and the wider effects on other immune cells. In the present study, 15 rel...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Nissimov, Nitzan, Hajiyeva, Zivar, Torke, Sebastian, Grondey, Katja, Brück, Wolfgang, Häusser-Kinzel, Silke, Weber, Martin S.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7568262/
https://ncbi.nlm.nih.gov/pubmed/32999069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2012249117
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