Dimethyl fumarate impairs differentiated B cells and fosters central nervous system integrity in treatment of multiple sclerosis

In multiple sclerosis (MS), the effect of dimethyl fumarate (DMF) treatment is primarily attributed to its capacity to dampen pathogenic T cells. Here, we tested whether DMF also modulates B cells, which are newly recognized key players in MS, and to which extent DMF restricts ongoing loss of oligod...

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Podrobná bibliografie
Vydáno v:Brain Pathol
Hlavní autoři: Traub, Jan, Traffehn, Sarah, Ochs, Jasmin, Häusser‐Kinzel, Silke, Stephan, Schirin, Scannevin, Robert, Brück, Wolfgang, Metz, Imke, Weber, Martin S.
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2019
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6849574/
https://ncbi.nlm.nih.gov/pubmed/30706542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bpa.12711
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