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Dimethyl fumarate impairs differentiated B cells and fosters central nervous system integrity in treatment of multiple sclerosis

In multiple sclerosis (MS), the effect of dimethyl fumarate (DMF) treatment is primarily attributed to its capacity to dampen pathogenic T cells. Here, we tested whether DMF also modulates B cells, which are newly recognized key players in MS, and to which extent DMF restricts ongoing loss of oligod...

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Detalhes bibliográficos
Publicado no:Brain Pathol
Main Authors: Traub, Jan, Traffehn, Sarah, Ochs, Jasmin, Häusser‐Kinzel, Silke, Stephan, Schirin, Scannevin, Robert, Brück, Wolfgang, Metz, Imke, Weber, Martin S.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6849574/
https://ncbi.nlm.nih.gov/pubmed/30706542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bpa.12711
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